Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 5/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420319 | 0.87 | CHEK1 (0.41) | ALDH1A1MAPTNPSR1HSD17B10MEN1 | |
| SCHEMBL3898671 | 0.77 | PARP1 (0.45) | ALDH1A1HSD17B10MEN1KMT2APARP1 | |
| SCHEMBL8662857 | 0.71 | PARP1 (0.50) | ALDH1A1HSD17B10PARP1KDM4ELMNA | |
| SCHEMBL23537356 | 0.69 | PARP1 (0.59) | ALDH1A1MAPTNPSR1HSD17B10MEN1 | |
| SCHEMBL29824193 | 0.69 | PARP1 (0.59) | ALDH1A1MAPTNPSR1HSD17B10MEN1 | |
| SCHEMBL23537530 | 0.69 | ALDH1A1 (0.47) | ALDH1A1MAPTNPSR1HSD17B10MEN1 | |
| SCHEMBL14178920 | 0.68 | BCHE (0.39) | ALDH1A1HSD17B10MEN1KMT2APARP1 | |
| SCHEMBL31180491 | 0.68 | KMT2A (0.46) | ALDH1A1MAPTNPSR1HSD17B10MEN1 | |
| SCHEMBL10287085 | 0.68 | KMT2A (0.46) | ALDH1A1MAPTNPSR1HSD17B10MEN1 | |
| SCHEMBL18663354 | 0.67 | CYP1A2 (0.38) | ALDH1A1MAPTHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736095-A | 9, 10-disubstituted phenanthrene compound and synthesis method thereof | 河南师范大学 | 2024-03-22 | — | — | CN | disclosed |