Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.43 |
| ▸ | SRC | P12931 | 5/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26620152 | 1.00 | ABL1 (0.43) | ABL1SRCDYRK1AALPLCYP1A2 | |
| SCHEMBL23147745 | 0.84 | NUDT1 (0.44) | NUDT1SYKKDM4E | |
| SCHEMBL29721792 | 0.84 | NUDT1 (0.44) | NUDT1SYKKDM4E | |
| SCHEMBL30226495 | 0.83 | ABL1 (0.45) | ABL1SRCALPLCYP1A2NUDT1 | |
| SCHEMBL899166 | 0.83 | ABL1 (0.45) | ABL1SRCALPLCYP1A2NUDT1 | |
| SCHEMBL7975640 | 0.83 | GLA (0.48) | ABL1SRCDYRK1ACYP1A2NUDT1 | |
| SCHEMBL22554309 | 0.83 | ABL1 (0.44) | ABL1SRCDYRK1ACYP1A2NUDT1 | |
| SCHEMBL30731054 | 0.83 | ABL1 (0.44) | ABL1SRCDYRK1ACYP1A2NUDT1 | |
| SCHEMBL23147741 | 0.83 | NUDT1 (0.43) | ABL1DYRK1ANUDT1 | |
| SCHEMBL29721951 | 0.83 | NUDT1 (0.43) | ABL1DYRK1ANUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916241-A | Spiro compounds | 阿斯利康(瑞典)有限公司 | 2024-04-19 | — | — | CN | disclosed |