Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29204861 | 0.91 | SMN1; SMN2 (0.61) | SMN1; SMN2LMNAMEN1KMT2ANPC1 | |
| SCHEMBL22866816 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAMEN1KMT2ANPC1 | |
| SCHEMBL29559882 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAMEN1KMT2ANPC1 | |
| SCHEMBL6924992 | 0.85 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAMEN1KMT2ANPC1 | |
| SCHEMBL29684781 | 0.83 | KDM4E (0.60) | SMN1; SMN2LMNAMEN1KMT2ANPC1 | |
| SCHEMBL11565430 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAMEN1KMT2ANPC1 | |
| SCHEMBL5003896 | 0.80 | KDM4E (0.64) | SMN1; SMN2LMNAMEN1KMT2ANPC1 | |
| SCHEMBL929698 | 0.80 | GAA (0.54) | SMN1; SMN2LMNAMEN1KMT2ANPC1 | |
| SCHEMBL12469762 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAMEN1KMT2ANPC1 | |
| SCHEMBL25244529 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2LMNAMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964652-A | Tetradentate phenol ether ligand-metal complex derived from naphthol, preparation method and olefin polymerization method | 中国科学院大连化学物理研究所 | 2024-05-03 | — | — | CN | disclosed |