Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30883372 | 1.00 | KDM4E (0.51) | KDM4EHPGDNPSR1L3MBTL1HTT | |
| SCHEMBL30883370 | 0.88 | KDM4E (0.51) | KDM4EHPGDNPSR1L3MBTL1HTT | |
| SCHEMBL26665755 | 0.83 | KDM4E (0.56) | KDM4EHPGDNPSR1L3MBTL1HTT | |
| SCHEMBL27211489 | 0.83 | MAPT (0.44) | KDM4EHPGDNPSR1L3MBTL1HTT | |
| SCHEMBL27211514 | 0.75 | CA1 (0.42) | KDM4EHPGDSMN1; SMN2HSD17B10MAPT | |
| SCHEMBL26665761 | 0.72 | KDM4E (0.59) | KDM4EHPGDNPSR1L3MBTL1HTT | |
| SCHEMBL24748614 | 0.71 | CYP1A2 (0.43) | KDM4EHPGDNPSR1L3MBTL1HTT | |
| SCHEMBL26665773 | 0.71 | KDM4E (0.56) | KDM4EHPGDNPSR1L3MBTL1HTT | |
| SCHEMBL26665762 | 0.71 | KDM4E (0.56) | KDM4EHPGDNPSR1L3MBTL1HTT | |
| SCHEMBL26665768 | 0.71 | HTT (0.61) | KDM4EHPGDNPSR1L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11976066-B1 | Substituted 7-amino-3-(substituted benzoyl)indolizine-1-carboxylates as anti-tubercular agents | King Faisal University (SA) | 2024-05-07 | — | — | US | claimed |
| US-11976066-B1 | Substituted 7-amino-3-(substituted benzoyl)indolizine-1-carboxylates as anti-tubercular agents | King Faisal University (SA) | 2024-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11976066-B1 | Substituted 7-amino-3-(substituted benzoyl)indolizine-1-carboxylates as anti-tubercular agents | BET1, INMT, IDO1 | KDM4E 878/4885HPGD 2045/4885NPSR1 4059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.