Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 4/20 | 0.58 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3086297 | 0.91 | SCD (0.56) | SCDDCTPP1CYP3A4CYP2D6 | |
| SCHEMBL3097878 | 0.88 | SCD (0.53) | SCDDCTPP1CYP3A4CYP2D6 | |
| SCHEMBL1815448 | 0.87 | SCD (0.68) | SCD | |
| SCHEMBL4252657 | 0.84 | SCD (0.62) | SCDCYP3A4CYP2D6 | |
| SCHEMBL3086437 | 0.84 | SCD (0.53) | SCDDCTPP1 | |
| SCHEMBL3097781 | 0.84 | SCD (0.57) | SCDCYP3A4CYP2D6 | |
| SCHEMBL3103939 | 0.83 | SCD (0.61) | SCDCYP3A4CYP2D6 | |
| SCHEMBL3092596 | 0.83 | SCD (0.53) | SCD | |
| SCHEMBL3094322 | 0.81 | SCD (0.57) | SCDCYP3A4CYP2D6 | |
| SCHEMBL3086714 | 0.81 | SCD (0.53) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799787-B2 | Heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase | MERCK FROSST CANADA LTD. (CA) | 2010-09-21 | — | — | US | disclosed |
| US-7799787-B2 | Heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase | MERCK FROSST CANADA LTD. (CA) | 2010-09-21 | — | — | US | disclosed |
| US-7799787-B2 | Heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase | MERCK FROSST CANADA LTD. (CA) | 2010-09-21 | — | — | US | disclosed |
| US-20090088431-A1 | Heteroaromatic Compounds as Inhibitors of Stearoyl-Coenzyme a Delta-9 Desaturase | MERCK FROSST CANADA LTD. | 2009-04-02 | — | — | US | disclosed |
| US-20090088431-A1 | Heteroaromatic Compounds as Inhibitors of Stearoyl-Coenzyme a Delta-9 Desaturase | MERCK FROSST CANADA LTD. | 2009-04-02 | — | — | US | disclosed |
| US-20090088431-A1 | Heteroaromatic Compounds as Inhibitors of Stearoyl-Coenzyme a Delta-9 Desaturase | MERCK FROSST CANADA LTD. | 2009-04-02 | — | — | US | disclosed |
| WO-2007071023-A1 | HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088431-A1 | Heteroaromatic Compounds as Inhibitors of Stearoyl-Coenzyme a Delta-9 Desaturase | SCD, SCD5, SREBF1 | SCD 1/4885DCTPP1 3017/4885CYP3A4 666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.