SCHEMBL30885909

SCHEMBL30885909

COc1cc2c(cc1Br)-c1c(c(C(=O)N(C)C(C)(C)C)nn1-c1cc(Cl)cc(Cl)c1)CO2

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ NR1H4 Q96RI1 5/20 0.35
▸ PDE7A Q13946 1/20 0.32
▸ PDE3A Q14432 1/20 0.32
▸ PDE10A Q9Y233 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.30
▸ RAD52 P43351 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17381611 1.00 NR1H4 (0.35) NR1H4PDE7APDE3APDE10AALDH1A1
SCHEMBL31236970 0.92 RAD52 (0.32) PDE7APDE3APDE10AALDH1A1RAD52
SCHEMBL17385321 0.92 CCNA2 (0.39) NR1H4ALDH1A1
SCHEMBL20988684 0.91 NR1H4 (0.35) NR1H4PDE7APDE3APDE10AALDH1A1
SCHEMBL17381600 0.90 NR1H4 (0.35) NR1H4PDE7APDE3APDE10A
SCHEMBL24758668 0.90 NR1H4 (0.36) NR1H4PDE7APDE3APDE10ARAD52
SCHEMBL19305847 0.88 NR1H4 (0.34) NR1H4PDE7APDE3APDE10A
SCHEMBL17381962 0.87 NR1H4 (0.38) NR1H4
SCHEMBL29539301 0.86 PDE7A (0.32) NR1H4PDE7APDE3APDE10A
SCHEMBL16334006 0.86 PDE7A (0.32) NR1H4PDE7APDE3APDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4598928-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF Radionetics Oncology, Inc. (US) 2025-08-13 — — EP disclosed
WO-2024077006-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2024-04-11 — — WO disclosed
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