Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30885909 | 0.90 | NR1H4 (0.35) | NR1H4RAD52PDE7APDE3APDE10A | |
| SCHEMBL17381611 | 0.90 | NR1H4 (0.35) | NR1H4RAD52PDE7APDE3APDE10A | |
| SCHEMBL20988684 | 0.90 | NR1H4 (0.35) | NR1H4RAD52PDE7APDE3APDE10A | |
| SCHEMBL19305847 | 0.87 | NR1H4 (0.34) | NR1H4PDE7APDE3APDE10A | |
| SCHEMBL17381962 | 0.85 | NR1H4 (0.38) | NR1H4 | |
| SCHEMBL19326314 | 0.85 | NR1H4 (0.34) | NR1H4RAD52 | |
| SCHEMBL17381563 | 0.85 | NR1H4 (0.32) | NR1H4 | |
| SCHEMBL17381560 | 0.85 | NR1H4 (0.32) | NR1H4 | |
| SCHEMBL17381566 | 0.85 | NR1H4 (0.32) | NR1H4 | |
| SCHEMBL19325983 | 0.85 | NR1H4 (0.32) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402929-A1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | TOCOPHERX INC (US) | 2022-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402929-A1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | FSHR, GNRHR, LHCGR | NR1H4 857/4885RAD52 4685/4885PDE7A 195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.