SCHEMBL30885995

SCHEMBL30885995

COc1cc2c(cc1-c1cccc(N=C=O)c1)-c1c(c(C(=O)N(C)C(C)(C)C)nn1-c1cc(Cl)cc(Cl)c1)CO2

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ NR1H4 Q96RI1 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30886126 0.92 NR1H4 (0.35) NR1H4
SCHEMBL17381574 0.89 NR1H4 (0.36) NR1H4
SCHEMBL30886010 0.88 NR1H4 (0.36) NR1H4
SCHEMBL17381595 0.87 PTGDR2 (0.35) NR1H4
SCHEMBL17382116 0.87 NR1H4 (0.42) NR1H4
SCHEMBL30681676 0.87 NR1H4 (0.42) NR1H4
SCHEMBL17381641 0.86 PDE2A (0.38) NR1H4
SCHEMBL30886348 0.86 CCNA2 (0.38) NR1H4
SCHEMBL30886104 0.84 NR1H4 (0.36) NR1H4
SCHEMBL17382131 0.83 NR1H4 (0.37) NR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4598928-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF Radionetics Oncology, Inc. (US) 2025-08-13 — — EP disclosed
WO-2024077006-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2024-04-11 — — WO disclosed
Send feedback