SCHEMBL30886010

SCHEMBL30886010

COc1cc2c(cc1-c1cccc(N)c1)-c1c(c(C(=O)N(C)C(C)(C)C)nn1-c1cc(Cl)cc(Cl)c1)CO2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR1H4 Q96RI1 3/20 0.36
▸ CNR2 P34972 1/20 0.32
▸ TUBB4A P04350 5/20 0.31
▸ TUBB P07437 5/20 0.31
▸ TUBA3C P0DPH7 5/20 0.31
▸ TUBA1B P68363 5/20 0.31
▸ TUBA4A P68366 5/20 0.31
▸ TUBB4B P68371 5/20 0.31
▸ TUBB3 Q13509 5/20 0.31
▸ TUBB2A Q13885 5/20 0.31
▸ TUBB8 Q3ZCM7 5/20 0.31
▸ TUBA3E Q6PEY2 5/20 0.31
▸ TUBA1A Q71U36 5/20 0.31
▸ TUBA1C Q9BQE3 5/20 0.31
▸ TUBB6 Q9BUF5 5/20 0.31
▸ TUBB2B Q9BVA1 5/20 0.31
▸ TUBB1 Q9H4B7 5/20 0.31
▸ CCNA2 P20248 1/20 0.31
▸ CDK2 P24941 1/20 0.31
▸ CCNA1 P78396 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17381574 0.92 NR1H4 (0.36) NR1H4CNR2MAPT
SCHEMBL30886104 0.92 NR1H4 (0.36) NR1H4
SCHEMBL17381641 0.91 PDE2A (0.38) NR1H4CNR2CCNA2CDK2CCNA1
SCHEMBL30681676 0.90 NR1H4 (0.42) NR1H4
SCHEMBL17382116 0.90 NR1H4 (0.42) NR1H4
SCHEMBL17381573 0.90 NR1H4 (0.35) NR1H4
SCHEMBL17381595 0.89 PTGDR2 (0.35) NR1H4GRM5
SCHEMBL17381591 0.88 NR1H4 (0.34) NR1H4
SCHEMBL30885995 0.88 NR1H4 (0.35) NR1H4
SCHEMBL17381593 0.86 NR1H4 (0.33) NR1H4SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4598928-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF Radionetics Oncology, Inc. (US) 2025-08-13 — — EP disclosed
WO-2024077006-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2024-04-11 — — WO disclosed
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