SCHEMBL30886147

SCHEMBL30886147

COc1cc2c(cc1Br)-c1c(c(C(=O)N3CCOCC3(C)C)nn1-c1cc(F)cc(F)c1)CO2

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ GRM5 P41594 2/20 0.35
▸ PIK3CD O00329 14/20 0.35
▸ PIK3R2 O00459 14/20 0.35
▸ PIK3CA P42336 14/20 0.35
▸ PIK3CB P42338 14/20 0.35
▸ PIK3CG P48736 14/20 0.35
▸ PIK3R5 Q8WYR1 14/20 0.35
▸ PIK3R3 Q92569 14/20 0.35
▸ UGCG Q16739 3/20 0.32
▸ GLA P06280 1/20 0.32
▸ KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30885924 0.91 GRM5 (0.37) GRM5PIK3CDPIK3R2PIK3CAPIK3CB
SCHEMBL17382275 0.88 PIK3CD (0.34) GRM5PIK3CDPIK3R2PIK3CAPIK3CB
SCHEMBL27123561 0.87 GRM5 (0.36) GRM5PIK3CDPIK3R2PIK3CAPIK3CB
SCHEMBL30759609 0.87 GRM5 (0.36) GRM5PIK3CDPIK3R2PIK3CAPIK3CB
SCHEMBL17783226 0.87 PIK3CD (0.36) GRM5PIK3CDPIK3R2PIK3CAPIK3CB
SCHEMBL17382281 0.86 PIK3CD (0.32) GRM5PIK3CDPIK3R2PIK3CAPIK3CB
SCHEMBL30886053 0.86 GRM5 (0.33) GRM5PIK3CDPIK3R2PIK3CAPIK3CB
SCHEMBL17382145 0.85 GRM5 (0.37) GRM5PIK3CDPIK3R2PIK3CAPIK3CB
SCHEMBL31236950 0.85 GRM5 (0.37) GRM5PIK3CDPIK3R2PIK3CAPIK3CB
SCHEMBL17382270 0.85 PIK3CD (0.35) GRM5PIK3CDPIK3R2PIK3CAPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137819-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY INC (US) 2026-05-21 — — US disclosed
EP-4598928-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF Radionetics Oncology, Inc. (US) 2025-08-13 — — EP disclosed
WO-2024077006-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2024-04-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137819-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF FSHR, GNRHR, LHCGR GRM5 1818/4885PIK3CD 4438/4885PIK3R2 2070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback