Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 6/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3079784 | 0.91 | PRKCA (0.51) | PRKCAMMP12SCN9ANR1I2KCNH2 | |
| SCHEMBL3095670 | 0.87 | PRKCA (0.42) | PRKCAMMP12SCN9ANR1I2KCNH2 | |
| SCHEMBL3087256 | 0.86 | PRKCA (0.48) | PRKCAMMP12SCN9ANR1I2KCNH2 | |
| SCHEMBL3083720 | 0.84 | PRKCA (0.42) | PRKCAMMP12SCN9ANR1I2KCNH2 | |
| SCHEMBL3083577 | 0.84 | KCNH2 (0.45) | PRKCAMMP12SCN9ANR1I2KCNH2 | |
| SCHEMBL3084480 | 0.84 | PRKCA (0.42) | PRKCAMMP12SCN9ANR1I2KCNH2 | |
| SCHEMBL3087641 | 0.83 | PRKCA (0.42) | PRKCAMMP12SCN9ANR1I2KCNH2 | |
| SCHEMBL3093288 | 0.80 | PRKCA (0.48) | PRKCAMMP12SCN9ANR1I2KCNH2 | |
| SCHEMBL4200779 | 0.80 | PRKCA (0.49) | PRKCAMMP12SCN9ANR1I2KCNH2 | |
| SCHEMBL3095848 | 0.77 | PRKCA (0.51) | PRKCAMMP12SCN9ANR1I2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7795247-B2 | Tetracyclic indole derivatives as antiviral agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2010-09-14 | — | — | US | disclosed |