Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30888336 | 0.95 | SMN1; SMN2 (0.38) | SMN1; SMN2NPC1RAB9APOLBGAA | |
| SCHEMBL29235539 | 0.88 | SMN1; SMN2 (0.39) | SMN1; SMN2NPC1RAB9APOLBGAA | |
| SCHEMBL29598635 | 0.84 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1RAB9APOLBGAA | |
| SCHEMBL29598733 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2NPC1RAB9APOLBGAA | |
| SCHEMBL29708341 | 0.75 | L3MBTL1 (0.45) | SMN1; SMN2NPC1RAB9APOLBGAA | |
| SCHEMBL29597649 | 0.71 | GAA (0.44) | SMN1; SMN2NPC1RAB9AGAACYP1A2 | |
| SCHEMBL29598527 | 0.71 | CYP1A2 (0.39) | SMN1; SMN2NPC1RAB9APOLBGAA | |
| SCHEMBL29597771 | 0.70 | CYP1A2 (0.42) | SMN1; SMN2NPC1RAB9AGAACYP1A2 | |
| SCHEMBL29598561 | 0.69 | CYP1A2 (0.41) | SMN1; SMN2NPC1RAB9AGAACYP1A2 | |
| SCHEMBL30888381 | 0.68 | CYP1A2 (0.40) | SMN1; SMN2NPC1RAB9AGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450283-B | 3, 6-Diamino-pyridazin-3-yl derivatives, pharmaceutical compositions containing them and their use as pro-apoptotic agents | 法国施维雅药厂 | 2024-05-07 | — | — | CN | disclosed |