Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 14/20 | 0.49 |
| ▸ | CCND1 | P24385 | 14/20 | 0.49 |
| ▸ | CCND3 | P30281 | 14/20 | 0.49 |
| ▸ | CDK6 | Q00534 | 14/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21522786 | 1.00 | CDK4 (0.49) | CDK4CCND1CCND3CDK6ACACB | |
| SCHEMBL21522664 | 0.82 | CDK4 (0.46) | CDK4CCND1CCND3CDK6L3MBTL1 | |
| SCHEMBL21522710 | 0.80 | CDK4 (0.66) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL30888977 | 0.80 | CDK4 (0.66) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL15742212 | 0.77 | CDK4 (0.40) | CDK4CCND1CCND3CDK6L3MBTL1 | |
| SCHEMBL20987140 | 0.77 | CDK4 (0.39) | CDK4CCND1CCND3CDK6ACACB | |
| SCHEMBL30040513 | 0.77 | CDK4 (0.39) | CDK4CCND1CCND3CDK6ACACB | |
| SCHEMBL21539304 | 0.75 | POLB (0.34) | CDK4CCND1CCND3CDK6ACACB | |
| SCHEMBL19836741 | 0.73 | ACACB (0.35) | CDK4CCND1CCND3CDK6ACACB | |
| SCHEMBL30039127 | 0.73 | ACACB (0.35) | CDK4CCND1CCND3CDK6ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118286225-A | 2-Amino-pyridine or 2-amino-pyrimidine derivatives as cyclin dependent kinase inhibitors | 辉瑞公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-112313219-B | 2-Amino-pyridine or 2-amino-pyrimidine derivatives as cyclin dependent kinase inhibitors | 辉瑞公司 | 2024-04-26 | — | — | CN | disclosed |