Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 20/20 | 0.66 |
| ▸ | CCND1 | P24385 | 20/20 | 0.66 |
| ▸ | CCND3 | P30281 | 20/20 | 0.66 |
| ▸ | CDK6 | Q00534 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21522710 | 1.00 | CDK4 (0.66) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL29268584 | 0.91 | CDK4 (0.56) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL21522659 | 0.86 | CDK4 (0.52) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL21522851 | 0.84 | CDK4 (0.77) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL21522731 | 0.80 | CDK4 (1.00) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL30888969 | 0.80 | CDK4 (0.49) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL21522786 | 0.80 | CDK4 (0.49) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL30889003 | 0.76 | CDK4 (0.45) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL29268589 | 0.76 | CDK4 (0.45) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL19836706 | 0.75 | CDK4 (0.54) | CDK4CCND1CCND3CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118286225-A | 2-Amino-pyridine or 2-amino-pyrimidine derivatives as cyclin dependent kinase inhibitors | 辉瑞公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-112313219-B | 2-Amino-pyridine or 2-amino-pyrimidine derivatives as cyclin dependent kinase inhibitors | 辉瑞公司 | 2024-04-26 | — | — | CN | disclosed |