Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 3/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30889347 | 0.94 | MAPT (0.42) | TLR8TYRMAPTHCAR2MEN1 | |
| SCHEMBL30889343 | 0.92 | MAPT (0.45) | TYRMAPTHCAR2MEN1KMT2A | |
| SCHEMBL30889348 | 0.92 | MAPT (0.45) | TYRMAPTHCAR2MEN1KMT2A | |
| SCHEMBL29958550 | 0.92 | MAPT (0.45) | TYRMAPTHCAR2MEN1KMT2A | |
| SCHEMBL5164704 | 0.78 | TLR8 (0.37) | TLR8MAPTSMN1; SMN2ALOX15ELANE | |
| SCHEMBL30318954 | 0.74 | HCAR2 (0.38) | TYRMAPTHCAR2MEN1KMT2A | |
| SCHEMBL31266381 | 0.71 | MAPT (0.45) | TLR8CTRCMAPTALDH1A1HCAR2 | |
| SCHEMBL27760658 | 0.71 | TDP1 (0.53) | CTRCMAPTALDH1A1HCAR2GAA | |
| SCHEMBL11682168 | 0.70 | TYR (0.50) | TLR8CTRCTYRMAPTMEN1 | |
| SCHEMBL3925033 | 0.70 | TLR8 (0.40) | TLR8MAPTALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881658-A | Two-step synthesis of pyrrole compounds from furan compounds | 切弗朗菲利浦化学公司 | 2024-04-12 | — | — | CN | disclosed |