Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ELANE | P08246 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30889343 | 1.00 | MAPT (0.45) | MAPTELANEALOX5ALOX15MEN1 | |
| SCHEMBL29958550 | 1.00 | MAPT (0.45) | MAPTELANEALOX5ALOX15MEN1 | |
| SCHEMBL30889347 | 0.98 | MAPT (0.42) | MAPTELANEALOX5ALOX15MEN1 | |
| SCHEMBL30889342 | 0.92 | TLR8 (0.40) | MAPTELANEALOX15MEN1TYR | |
| SCHEMBL30318954 | 0.82 | HCAR2 (0.38) | MAPTELANEALOX5ALOX15MEN1 | |
| SCHEMBL27794737 | 0.75 | PPARA (0.48) | MAPTELANEALOX15HCAR2 | |
| SCHEMBL27782222 | 0.73 | TDP1 (0.50) | MAPTMEN1KMT2ATDP1 | |
| SCHEMBL9581030 | 0.72 | ALOX5 (0.46) | MAPTALOX5ALOX15MEN1TP53 | |
| SCHEMBL20122065 | 0.72 | MAPT (0.45) | MAPTELANEALOX5ALOX15TP53 | |
| SCHEMBL10878735 | 0.72 | EPHX2 (0.57) | MAPTELANEALOX5ALOX15TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881658-A | Two-step synthesis of pyrrole compounds from furan compounds | 切弗朗菲利浦化学公司 | 2024-04-12 | — | — | CN | disclosed |