Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24190029 | 0.84 | KDM4E (0.51) | KDM4EHSD17B10GPR35ALDH1A1HPGD | |
| SCHEMBL22647495 | 0.83 | KDM4E (0.53) | KDM4EHSD17B10GPR35ALDH1A1HPGD | |
| SCHEMBL2003980 | 0.82 | KDM4E (0.53) | KDM4EHSD17B10GPR35ALDH1A1HPGD | |
| SCHEMBL30310312 | 0.78 | KDM4E (0.59) | KDM4EHSD17B10GPR35ALDH1A1HPGD | |
| SCHEMBL2762336 | 0.78 | KDM4E (0.59) | KDM4EHSD17B10GPR35ALDH1A1HPGD | |
| SCHEMBL145350 | 0.77 | FLT3 (0.58) | KDM4EHSD17B10GPR35ALDH1A1HPGD | |
| SCHEMBL30097060 | 0.77 | FLT3 (0.58) | KDM4EHSD17B10GPR35ALDH1A1HPGD | |
| SCHEMBL27518065 | 0.77 | KDM4E (0.57) | KDM4EHSD17B10GPR35ALDH1A1HPGD | |
| SCHEMBL17034691 | 0.76 | CYP1A2 (0.47) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL2806087 | 0.75 | KDM4E (0.59) | KDM4EHSD17B10GPR35ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107778-A1 | NOVEL PROTEASE INHIBITORS FOR TREATMENT OF CORONAVIRUS INFECTIONS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-05-23 | — | — | WO | disclosed |