SCHEMBL2806087

SCHEMBL2806087

O=C(O)c1cc2c(C(=O)O)cccc2[nH]1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.59
HSD17B10 Q99714 3/20 0.59
ALDH1A1 P00352 2/20 0.59
HPGD P15428 2/20 0.59
GRIN1 Q05586 2/20 0.59
MEN1 O00255 1/20 0.59
GRIN2D O15399 1/20 0.59
GRIN3B O60391 1/20 0.59
CYP1A2 P05177 1/20 0.59
GLA P06280 1/20 0.59
GAA P10253 1/20 0.59
MAPK1 P28482 1/20 0.59
CYP2C19 P33261 1/20 0.59
AHR P35869 1/20 0.59
CHRNA7 P36544 1/20 0.59
KMT2A Q03164 1/20 0.59
GRIN2A Q12879 1/20 0.59
GRIN2B Q13224 1/20 0.59
GRIN2C Q14957 1/20 0.59
GRIN3A Q8TCU5 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29721596 1.00 KDM4E (0.59) KDM4EHSD17B10ALDH1A1HPGDGRIN1
Water SCHEMBL8560785 0.96 KDM4E (0.56) KDM4EHSD17B10ALDH1A1HPGDGRIN1
SCHEMBL22621690 0.88 HRH4 (0.60) KDM4EHSD17B10ALDH1A1HPGDGRIN1
SCHEMBL28291600 0.88 KDM4E (0.54) KDM4EHSD17B10ALDH1A1HPGDGRIN1
SCHEMBL19643543 0.85 HRH4 (0.48) KDM4EHSD17B10ALDH1A1HPGDGRIN1
SCHEMBL2006392 0.85 KDM4E (0.55) KDM4EHSD17B10ALDH1A1HPGDGRIN1
SCHEMBL5618186 0.84 KDM4E (0.50) KDM4EHSD17B10ALDH1A1HPGDGRIN1
SCHEMBL2762336 0.81 KDM4E (0.59) KDM4EHSD17B10ALDH1A1HPGDGRIN1
SCHEMBL30189206 0.81 FLT3 (0.60) KDM4EHSD17B10ALDH1A1HPGDGRIN1
SCHEMBL3417091 0.81 FLT3 (0.60) KDM4EHSD17B10ALDH1A1HPGDGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114736129-A Dicarboxylic acid-based eutectic solvent and preparation method and application thereof 中国科学院成都有机化学有限公司 2022-07-12 CN claimed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
EP-4204100-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE L'OREAL (FR) 2023-07-05 EP disclosed
CN-116322616-A Hair lightening compositions providing damage protection and sensory benefits and methods of use 欧莱雅 2023-06-23 CN disclosed
CN-114736129-B Dicarboxylic acid-based eutectic solvent and preparation method and application thereof 中国科学院成都有机化学有限公司 2023-03-31 CN disclosed
US-11559474-B2 Hair lightening compositions and methods of use L'OREAL (FR) 2023-01-24 US disclosed
CN-114736129-A Dicarboxylic acid-based eutectic solvent and preparation method and application thereof 中国科学院成都有机化学有限公司 2022-07-12 CN disclosed
WO-2022047081-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE HENRY DEREK (US) 2022-03-03 WO disclosed
CN-112978709-A Carbon quantum dot precursor composition, carbon quantum dot and preparation method thereof 中国科学院大连化学物理研究所 2021-06-18 CN disclosed
WO-2018128678-A2 COMPOSITIONS AND METHODS FOR RESTRUCTURING CHEMICALLY TREATED HAIR L'OREAL (FR) 2018-07-12 WO disclosed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US disclosed
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION L'OREAL (FR) 2009-01-29 US disclosed
WO-2004096210-A1 ACYLATED INDOLINE AND TETRAHYDROQUINOLINE DERIVATIVES AS HCV INHIBITORS GLAXO GROUP LIMITED (GB) 2004-11-11 WO disclosed
EP-0603557-B1 Catalyst compositions and catalytic processes PHILLIPS PETROLEUM CO (US) 1997-07-30 EP disclosed
US-5461126-A Process of polymerizing olefins using organonickel catalyst compositions PHILLIPS PETROLEUM COMPANY (US) 1995-10-24 US disclosed
US-5332708-A Ethylene polymerization catalyst, organonickel compound and a heterocyclic nitrogen compound PHILLIPS PETROLEUM COMPANY (US) 1994-07-26 US disclosed
EP-0603557-A1 Catalyst compositions and catalytic processes PHILLIPS PETROLEUM COMPANY (US) 1994-06-29 EP disclosed
US-4093622-A Pyridine esters of cyclopropane-carboxylic acid ZOECON CORPORATION (US) 1978-06-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 KDM4E 2504/4885HSD17B10 71/4885ALDH1A1 1901/4885
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION CUTA, SYMPK, TPRKB KDM4E 1615/4885HSD17B10 2366/4885ALDH1A1 4765/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA KDM4E 1109/4885HSD17B10 47/4885ALDH1A1 1510/4885
US-11559474-B2 Hair lightening compositions and methods of use TYR, ALAD, CYBA KDM4E 2585/4885HSD17B10 671/4885ALDH1A1 448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.