Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | ESR1 | P03372 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541885 | 0.88 | ESR1 (0.62) | ALDH1A1ESR1TDP1TSHRCHRM1 | |
| Propylparaben SCHEMBL276143 | 0.82 | ESR1 (0.73) | ALDH1A1ESR1TDP1TSHRCHRM1 | |
| SCHEMBL3451817 | 0.79 | TSHR (0.64) | ALDH1A1ESR1TDP1TSHRCHRM1 | |
| SCHEMBL3088949 | 0.79 | TSHR (0.48) | ALDH1A1ESR1TDP1TSHRCHRM1 | |
| SCHEMBL1656743 | 0.77 | CA12 (0.74) | ALDH1A1ESR1TDP1TSHRCA12 | |
| SCHEMBL27659926 | 0.77 | TSHR (0.60) | ALDH1A1ESR1TSHRCA12CA1 | |
| SCHEMBL11635759 | 0.76 | SERPINE1 (0.57) | ALDH1A1ESR1TDP1TSHRCHRM1 | |
| SCHEMBL10569979 | 0.76 | ALDH1A1 (0.65) | ALDH1A1ESR1TDP1TSHRCHRM1 | |
| SCHEMBL11149829 | 0.75 | ESR1 (0.61) | ALDH1A1ESR1TDP1TSHRCHRM1 | |
| SCHEMBL10487722 | 0.75 | ALDH1A1 (0.54) | ALDH1A1ESR1TDP1TSHRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803906-B2 | Composition comprising an angiogenesis related protein | GENE SIGNAL INTERNATIONAL SA (CH) | 2010-09-28 | — | — | US | claimed |