Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26884312 | 0.89 | KCNA3 (0.36) | PIK3CARAB9APOLBKCNA3AKT1 | |
| SCHEMBL27129809 | 0.89 | KCNA3 (0.36) | PIK3CARAB9APOLBKCNA3AKT1 | |
| SCHEMBL26662568 | 0.87 | PIK3CA (0.44) | PIK3CAAKT1AKT2AKT3PIK3CD | |
| SCHEMBL26662576 | 0.87 | PIK3CA (0.44) | PIK3CAAKT1AKT2AKT3PIK3CD | |
| SCHEMBL30928518 | 0.82 | POLB (0.36) | PIK3CARAB9APOLBAKT1AKT2 | |
| SCHEMBL24912998 | 0.82 | ALDH1A1 (0.49) | PIK3CARAB9AAKT1AKT2AKT3 | |
| SCHEMBL31035409 | 0.82 | ALDH1A1 (0.49) | PIK3CARAB9AAKT1AKT2AKT3 | |
| SCHEMBL30893165 | 0.82 | ALDH1A1 (0.49) | PIK3CARAB9AAKT1AKT2AKT3 | |
| SCHEMBL26662592 | 0.82 | ALDH1A1 (0.49) | PIK3CARAB9AAKT1AKT2AKT3 | |
| SCHEMBL30090417 | 0.81 | PIK3CA (0.62) | PIK3CAAKT1AKT2AKT3PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4611899-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | Petra Pharma Corporation (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024097172-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | PETRA PHARMA CORPORATION (US) | 2024-05-10 | — | — | WO | disclosed |