Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 5/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 11/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 11/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 11/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.35 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26662391 | 0.89 | PIK3CA (0.44) | PIK3CAPIK3CDPIK3CBPIK3CGCSNK2A2 | |
| SCHEMBL30584369 | 0.89 | PIK3CA (0.44) | PIK3CAPIK3CDPIK3CBPIK3CGCSNK2A2 | |
| SCHEMBL26662394 | 0.89 | PIK3CA (0.44) | PIK3CAPIK3CDPIK3CBPIK3CGCSNK2A2 | |
| SCHEMBL27132735 | 0.86 | PIK3CA (0.50) | PIK3CAPIK3CDPIK3CBPIK3CGPRKDC | |
| SCHEMBL27008344 | 0.86 | PIK3CA (0.50) | PIK3CAPIK3CDPIK3CBPIK3CGPRKDC | |
| SCHEMBL30928402 | 0.81 | ACLY (0.37) | PIK3CAACLY | |
| SCHEMBL30928408 | 0.81 | ACLY (0.37) | PIK3CAACLY | |
| SCHEMBL30584366 | 0.81 | PIK3CA (0.43) | PIK3CAPIK3CDPIK3CBPIK3CGCSNK2A2 | |
| SCHEMBL26662622 | 0.81 | PIK3CA (0.43) | PIK3CAPIK3CDPIK3CBPIK3CGCSNK2A2 | |
| SCHEMBL26662615 | 0.81 | PIK3CA (0.43) | PIK3CAPIK3CDPIK3CBPIK3CGCSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4611899-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | Petra Pharma Corporation (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024097172-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | PETRA PHARMA CORPORATION (US) | 2024-05-10 | — | — | WO | disclosed |