SCHEMBL30889641

SCHEMBL30889641

Cc1ccc2oc(C3CC3)c(C)c(=O)c2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPG P10696 1/20 0.46
SIGMAR1 Q99720 1/20 0.44
MAPT P10636 7/20 0.43
KDM4E B2RXH2 6/20 0.43
ALDH1A1 P00352 5/20 0.42
NPC1 O15118 5/20 0.42
CSNK2A2 P19784 4/20 0.42
CSNK2B P67870 4/20 0.42
CSNK2A1 P68400 4/20 0.42
RAB9A P51151 4/20 0.42
HPGD P15428 4/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
TP53 P04637 3/20 0.42
HTT P42858 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
TSHR P16473 1/20 0.41
HSD17B10 Q99714 3/20 0.40
CYP3A4 P08684 2/20 0.40
PKM P14618 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1611070 0.75 ALPG (0.59) ALPGMAPTKDM4EALDH1A1NPC1
SCHEMBL6471093 0.73 ALPG (0.67) ALPGMAPTKDM4EALDH1A1NPC1
SCHEMBL31035360 0.73 ESR1 (0.37) SIGMAR1MAPTALDH1A1CSNK2A2CSNK2B
SCHEMBL31035264 0.72 ALPG (0.49) ALPGMAPTKDM4EALDH1A1NPC1
SCHEMBL31035035 0.71 CSNK2A2 (0.51) ALPGMAPTKDM4EALDH1A1NPC1
SCHEMBL31217594 0.71 ALPG (0.48) ALPGMAPTKDM4EALDH1A1NPC1
SCHEMBL31035222 0.70 KDM4E (0.34) SIGMAR1MAPTKDM4EALDH1A1NPC1
SCHEMBL9980172 0.69 ALPG (0.53) ALPGMAPTKDM4EALDH1A1NPC1
SCHEMBL31035685 0.69 PIK3CA (0.36) SIGMAR1KMT2A
SCHEMBL30889677 0.69 PIK3CA (0.38) SIGMAR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4680612-A1 CHEMICAL COMPOUNDS AN2 Therapeutics, Inc. (US) 2026-01-21 EP disclosed
EP-4611899-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE Petra Pharma Corporation (US) 2025-09-10 EP disclosed
WO-2024192309-A1 CHEMICAL COMPOUNDS REACTIVE BIOSCIENCES, INC. (US) 2024-09-19 WO disclosed
WO-2024097172-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE PETRA PHARMA CORPORATION (US) 2024-05-10 WO disclosed