Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 9/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30373780 | 0.91 | PIK3CA (0.35) | PIK3CAAKT1AKT2AKT3 | |
| SCHEMBL25178376 | 0.91 | PIK3CA (0.35) | PIK3CAAKT1AKT2AKT3 | |
| SCHEMBL31035499 | 0.87 | PIK3CA (0.38) | PIK3CAAKT1AKT2AKT3SIGMAR1 | |
| SCHEMBL30889677 | 0.87 | PIK3CA (0.38) | PIK3CAAKT1AKT2AKT3SIGMAR1 | |
| SCHEMBL25184861 | 0.86 | PIK3CA (0.41) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL30373211 | 0.86 | PIK3CA (0.41) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL25679258 | 0.81 | PIK3CA (0.40) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL31035360 | 0.81 | ESR1 (0.37) | SIGMAR1KMT2A | |
| SCHEMBL30889697 | 0.79 | PIK3CB (0.33) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL25181501 | 0.78 | PIK3CA (0.37) | PIK3CAAKT1AKT2AKT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680612-A1 | CHEMICAL COMPOUNDS | AN2 Therapeutics, Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| WO-2024192309-A1 | CHEMICAL COMPOUNDS | REACTIVE BIOSCIENCES, INC. (US) | 2024-09-19 | — | — | WO | disclosed |