Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31316450 | 0.73 | MAPT (0.74) | KMT2ACSNK2A2CSNK2BCSNK2A1MAPT | |
| SCHEMBL29171535 | 0.73 | MAPT (0.74) | KMT2ACSNK2A2CSNK2BCSNK2A1MAPT | |
| SCHEMBL30742014 | 0.72 | KMT2A (0.54) | KMT2ACSNK2A2CSNK2BCSNK2A1MAPT | |
| SCHEMBL1611070 | 0.70 | ALPG (0.59) | KMT2ACSNK2A2CSNK2BCSNK2A1MAPT | |
| SCHEMBL30742511 | 0.69 | MAPT (0.53) | KMT2ACSNK2A2CSNK2BCSNK2A1MAPT | |
| SCHEMBL30742368 | 0.68 | KMT2A (0.47) | KMT2ACSNK2A2CSNK2BCSNK2A1MAPT | |
| SCHEMBL6471093 | 0.68 | ALPG (0.67) | KMT2ACSNK2A2CSNK2BCSNK2A1MAPT | |
| SCHEMBL31035264 | 0.67 | ALPG (0.49) | KMT2ACSNK2A2CSNK2BCSNK2A1MAPT | |
| SCHEMBL30928529 | 0.67 | MAPT (0.41) | KMT2ACSNK2A2CSNK2BCSNK2A1MAPT | |
| SCHEMBL6646356 | 0.67 | AKR1B1 (0.59) | KMT2AMAPTKDM4ETP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4611899-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | Petra Pharma Corporation (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024097172-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | PETRA PHARMA CORPORATION (US) | 2024-05-10 | — | — | WO | disclosed |