Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 14/20 | 0.51 |
| ▸ | ESR1 | P03372 | 6/20 | 0.49 |
| ▸ | WIZ | O95785 | 2/20 | 0.48 |
| ▸ | IKZF2 | Q9UKS7 | 3/20 | 0.47 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.46 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24206987 | 0.93 | CRBN (0.54) | CRBNESR1WIZIKZF2IKZF1 | |
| SCHEMBL31726811 | 0.89 | CRBN (0.52) | CRBNESR1WIZIKZF2IKZF1 | |
| SCHEMBL22498388 | 0.89 | CRBN (0.52) | CRBNESR1WIZIKZF2IKZF1 | |
| SCHEMBL30906292 | 0.88 | CRBN (0.57) | CRBNESR1WIZIKZF2IKZF1 | |
| SCHEMBL27194328 | 0.88 | CRBN (0.52) | CRBNESR1WIZIKZF2IKZF1 | |
| SCHEMBL30828152 | 0.88 | CRBN (0.52) | CRBNESR1WIZIKZF2IKZF1 | |
| SCHEMBL30906245 | 0.88 | ESR1 (0.53) | CRBNESR1WIZIKZF2IKZF1 | |
| SCHEMBL30889713 | 0.87 | CRBN (0.57) | CRBNESR1WIZIKZF2IKZF1 | |
| SCHEMBL30822427 | 0.87 | CRBN (0.54) | CRBNESR1WIZGSPT1IKZF3 | |
| SCHEMBL31586617 | 0.86 | CRBN (0.52) | CRBNESR1WIZIKZF2IKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4611901-A1 | RET-LDD PROTEIN DEGRADERS | Bristol-Myers Squibb Company (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024097989-A1 | RET-LDD PROTEIN DEGRADERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-10 | — | — | WO | disclosed |