Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 11/20 | 0.57 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.52 |
| ▸ | IKZF2 | Q9UKS7 | 6/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.49 |
| ▸ | WIZ | O95785 | 1/20 | 0.49 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24207552 | 0.93 | CRBN (0.61) | CRBNCSNK1A1IKZF2ESR1IKZF1 | |
| SCHEMBL31586460 | 0.93 | CRBN (0.61) | CRBNCSNK1A1IKZF2ESR1IKZF1 | |
| SCHEMBL30889711 | 0.92 | CRBN (0.54) | CRBNCSNK1A1IKZF2ESR1IKZF1 | |
| SCHEMBL31586364 | 0.88 | CRBN (0.55) | CRBNCSNK1A1IKZF2ESR1IKZF1 | |
| SCHEMBL30889706 | 0.87 | CRBN (0.51) | CRBNCSNK1A1IKZF2ESR1IKZF1 | |
| SCHEMBL30906253 | 0.87 | CRBN (0.63) | CRBNCSNK1A1IKZF2ESR1IKZF1 | |
| SCHEMBL30828180 | 0.86 | CRBN (0.58) | CRBNCSNK1A1IKZF2ESR1IKZF1 | |
| SCHEMBL27194407 | 0.86 | CRBN (0.58) | CRBNCSNK1A1IKZF2ESR1IKZF1 | |
| SCHEMBL30985120 | 0.86 | CRBN (0.58) | CRBNCSNK1A1IKZF2ESR1WIZ | |
| SCHEMBL22498051 | 0.86 | CRBN (0.59) | CRBNCSNK1A1IKZF2IKZF1WIZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4611901-A1 | RET-LDD PROTEIN DEGRADERS | Bristol-Myers Squibb Company (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024097989-A1 | RET-LDD PROTEIN DEGRADERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-10 | — | — | WO | disclosed |