SCHEMBL30890396

N=C(N)NCCC[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O

nearest known ligand 0.78

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	16/20	0.78

▸	NPY1R	P25929	10/20	0.78

▸	NPY5R	Q15761	9/20	0.78

▸	NPY2R	P49146	6/20	0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30890408	1.00	NPY4R (0.78)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL31674339	0.99	NPY4R (0.77)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL29641186	0.99	NPY4R (0.77)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL29641176	0.99	NPY4R (0.77)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL29461962	0.97	NPY4R (0.80)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL29483774	0.96	NPY4R (0.73)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL8975469	0.96	NPY4R (0.73)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL29641194	0.94	NPY4R (0.76)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL29641019	0.94	NPY4R (0.76)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL30540725	0.94	NPY4R (0.73)	NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3858850-B1	NONAPEPTIDE PREVENTING INCREASED HYPERPERMEABILITY OF VASCULAR ENDOTHELIUM	FEDERALNOYE GOSUDARSTVENNOE BUDGETNOE UCHREZHDENIE NAC MEDICINSKIY ISSLEDOVATELSKIY CENTR KARDIOLOGI (RU)	2024-02-28	—	—	EP	disclosed