Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 14/20 | 0.53 |
| ▸ | EGFR | P00533 | 11/20 | 0.53 |
| ▸ | AURKA | O14965 | 3/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.49 |
| ▸ | TEK | Q02763 | 1/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 3/20 | 0.47 |
| ▸ | FLT4 | P35916 | 3/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26101303 | 0.88 | AURKA (0.54) | KDREGFRAURKAAURKBPDGFRB | |
| SCHEMBL30394371 | 0.88 | AURKA (0.54) | KDREGFRAURKAAURKBPDGFRB | |
| SCHEMBL30891798 | 0.82 | EGFR (0.61) | KDREGFRAURKAAURKBPDGFRB | |
| SCHEMBL31137798 | 0.79 | AURKA (0.57) | KDREGFRAURKAAURKBPDGFRB | |
| SCHEMBL26135569 | 0.79 | AURKA (0.57) | KDREGFRAURKAAURKBPDGFRB | |
| SCHEMBL26135146 | 0.79 | AURKA (0.57) | KDREGFRAURKAAURKBPDGFRB | |
| SCHEMBL30394263 | 0.78 | EGFR (0.55) | KDREGFRAURKAAURKBPDGFRB | |
| SCHEMBL26102199 | 0.76 | KDR (0.57) | KDREGFRAURKAAURKBPDGFRB | |
| SCHEMBL30394367 | 0.76 | AURKA (0.52) | KDREGFRAURKAAURKBPDGFRB | |
| SCHEMBL26103749 | 0.76 | AURKA (0.52) | KDREGFRAURKAAURKBPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201909-A | Quinazoline derivative compound and use thereof | 株式会社沃若诺伊 | 2024-06-14 | — | — | CN | disclosed |