Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.61 |
| ▸ | KDR | P35968 | 15/20 | 0.61 |
| ▸ | KIT | P10721 | 3/20 | 0.55 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.51 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 2/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.51 |
| ▸ | FLT4 | P35916 | 2/20 | 0.51 |
| ▸ | TEK | Q02763 | 2/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.51 |
| ▸ | RET | P07949 | 1/20 | 0.51 |
| ▸ | KIF5B | P33176 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30891764 | 0.84 | KDR (0.59) | EGFRKDRKITAURKAERBB2 | |
| SCHEMBL26099266 | 0.84 | KDR (0.59) | EGFRKDRKITAURKAERBB2 | |
| SCHEMBL30891780 | 0.82 | KDR (0.53) | EGFRKDRKITAURKAPDGFRB | |
| SCHEMBL26101960 | 0.78 | KDR (0.54) | EGFRKDRKITEHMT2EHMT1 | |
| SCHEMBL30891810 | 0.78 | KDR (0.55) | EGFRKDRKITEHMT2EHMT1 | |
| SCHEMBL19258107 | 0.78 | KDR (0.73) | EGFRKDRKITAURKAERBB2 | |
| SCHEMBL26101967 | 0.78 | KDR (0.55) | EGFRKDRKITEHMT2EHMT1 | |
| SCHEMBL31137829 | 0.77 | KDR (0.57) | EGFRKDRKITAURKAERBB2 | |
| SCHEMBL26098307 | 0.77 | KDR (0.57) | EGFRKDRKITAURKAERBB2 | |
| SCHEMBL26101510 | 0.77 | KDR (0.53) | EGFRKDRKITAURKAERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201909-A | Quinazoline derivative compound and use thereof | 株式会社沃若诺伊 | 2024-06-14 | — | — | CN | disclosed |