Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.58 |
| ▸ | MAOB | P27338 | 4/20 | 0.58 |
| ▸ | PTGIR | P43119 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5429182 | 0.98 | MAOA (0.55) | MAOAMAOBPTGIRMAPK1HTT | |
| SCHEMBL13609520 | 0.93 | MAOA (0.50) | MAOAMAOBPTGIRMAPK1HTT | |
| SCHEMBL1745003 | 0.89 | MAOB (0.44) | MAOAMAOBPTGIRMAPK1SMN1; SMN2 | |
| SCHEMBL23295277 | 0.86 | MAOA (0.65) | MAOAMAOBPTGIRMAPK1SMN1; SMN2 | |
| SCHEMBL5215573 | 0.79 | MAOA (0.42) | MAOAMAOBPTGIRSMN1; SMN2KMT2A | |
| SCHEMBL1939589 | 0.79 | MAOA (0.44) | MAOAMAOBHTTRAB9ANPC1 | |
| SCHEMBL30939414 | 0.79 | MAOB (0.44) | MAOAMAOBMAPK1SMN1; SMN2CYP2A6 | |
| SCHEMBL23639396 | 0.78 | MAOA (0.58) | MAOAMAOBPTGIRRAB9ANPC1 | |
| SCHEMBL12218337 | 0.78 | MAOA (0.58) | MAOAMAOBPTGIRMAPK1HTT | |
| SCHEMBL11557522 | 0.78 | MAOA (0.58) | MAOAMAOBPTGIRRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117897484-A | Antisense oligonucleotides and their use for treating neurodegenerative disorders | 卫材R&D管理有限公司 | 2024-04-16 | — | — | CN | disclosed |