Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 12/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 12/20 | 0.44 |
| ▸ | EGFR | P00533 | 6/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30893202 | 1.00 | IRAK4 (0.45) | IRAK4DDB1CRBNEGFRMMP1 | |
| SCHEMBL30893227 | 1.00 | IRAK4 (0.45) | IRAK4DDB1CRBNEGFRMMP1 | |
| SCHEMBL30569047 | 0.90 | DDB1 (0.46) | IRAK4DDB1CRBNEGFR | |
| SCHEMBL30893229 | 0.89 | IRAK4 (0.44) | IRAK4DDB1CRBN | |
| SCHEMBL21069281 | 0.89 | IRAK4 (0.44) | IRAK4DDB1CRBN | |
| SCHEMBL30893291 | 0.89 | IRAK4 (0.44) | IRAK4DDB1CRBN | |
| SCHEMBL25959886 | 0.88 | CRBN (0.51) | IRAK4DDB1CRBNEGFR | |
| Trifluoroacetic Acid SCHEMBL30392723 | 0.88 | DDB1 (0.44) | IRAK4DDB1CRBNEGFR | |
| SCHEMBL21069639 | 0.88 | DDB1 (0.46) | IRAK4DDB1CRBNEGFR | |
| SCHEMBL21070239 | 0.88 | DDB1 (0.46) | IRAK4DDB1CRBNEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097948-A1 | DEGRADERS OF MDM2 AND USES THEREOF | ROIVANT DISCOVERY, INC. (US) | 2024-05-10 | — | — | WO | disclosed |