Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 12/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.47 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30893267 | 0.98 | CRBN (0.54) | CRBNDDB1STAT3HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL30893302 | 0.98 | CRBN (0.54) | CRBNDDB1STAT3HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL30893274 | 0.98 | CRBN (0.54) | CRBNDDB1STAT3HDAC3HDAC4 | |
| SCHEMBL30893238 | 0.90 | CRBN (0.54) | CRBNDDB1STAT3HDAC3HDAC4 | |
| SCHEMBL27254175 | 0.89 | CRBN (0.55) | CRBNDDB1STAT3HDAC3HDAC4 | |
| SCHEMBL30751204 | 0.89 | CRBN (0.59) | CRBNDDB1STAT3ALDH1A1CHRM2 | |
| SCHEMBL24142096 | 0.89 | CRBN (0.53) | CRBNDDB1STAT3HDAC3HDAC1 | |
| SCHEMBL24458971 | 0.89 | CRBN (0.53) | CRBNDDB1STAT3HDAC3HDAC1 | |
| SCHEMBL27254174 | 0.89 | CRBN (0.55) | CRBNDDB1STAT3HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL30893273 | 0.88 | CRBN (0.52) | CRBNDDB1STAT3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097948-A1 | DEGRADERS OF MDM2 AND USES THEREOF | ROIVANT DISCOVERY, INC. (US) | 2024-05-10 | — | — | WO | disclosed |