Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 4/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30893186 | 0.94 | CRBN (0.59) | CRBNDDB1STAT3BRD9TRIM24 | |
| SCHEMBL23705538 | 0.91 | CRBN (0.57) | CRBNDDB1LRRK2IRAK4 | |
| SCHEMBL30058679 | 0.91 | CRBN (0.57) | CRBNDDB1LRRK2IRAK4 | |
| SCHEMBL29617105 | 0.89 | CRBN (0.59) | CRBNDDB1LRRK2IRAK4 | |
| SCHEMBL23729950 | 0.89 | CRBN (0.59) | CRBNDDB1LRRK2IRAK4 | |
| SCHEMBL29617100 | 0.89 | CRBN (0.59) | CRBNDDB1LRRK2IRAK4 | |
| SCHEMBL26813914 | 0.86 | STAT3 (0.59) | CRBNDDB1STAT3TRIM24CDK12 | |
| SCHEMBL30288371 | 0.86 | STAT3 (0.59) | CRBNDDB1STAT3TRIM24CDK12 | |
| Hydrochloric Acid SCHEMBL30893216 | 0.85 | CRBN (0.49) | CRBNDDB1STAT3BRD9TRIM24 | |
| SCHEMBL23317936 | 0.82 | CRBN (0.71) | CRBNDDB1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097948-A1 | DEGRADERS OF MDM2 AND USES THEREOF | ROIVANT DISCOVERY, INC. (US) | 2024-05-10 | — | — | WO | disclosed |