Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 15/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | INSR | P06213 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | LYN | P07948 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | MARK3 | P27448 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29182326 | 1.00 | LCK (0.38) | LCKKDRTEKNR1H4ROCK2 | |
| SCHEMBL30893379 | 0.89 | NR1H4 (0.37) | LCKKDRTEKNR1H4FABP1 | |
| SCHEMBL29182317 | 0.89 | NR1H4 (0.37) | LCKKDRTEKNR1H4FABP1 | |
| SCHEMBL29182329 | 0.87 | RET (0.49) | NR1H4RETFTOFABP1 | |
| SCHEMBL30893390 | 0.87 | RET (0.49) | NR1H4RETFTOFABP1 | |
| SCHEMBL29182324 | 0.85 | RET (0.41) | NR1H4RETFABP1FABP4 | |
| SCHEMBL30893380 | 0.85 | RET (0.38) | NR1H4RET | |
| SCHEMBL29182337 | 0.85 | RET (0.38) | NR1H4RET | |
| SCHEMBL30341063 | 0.85 | RET (0.41) | NR1H4RETFABP1FABP4 | |
| SCHEMBL30341066 | 0.83 | DGAT1 (0.37) | NR1H4RETFTOFABP1FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813308-A | Nitrogen-containing condensed ring compound, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2024-04-02 | — | — | CN | disclosed |