Phthalic Acid

Phthalic Acid

SCHEMBL30894713

C=C(C)C(=O)O.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.67

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.67
ALOX15 P16050 1/20 0.67
AKR1C3 P42330 2/20 0.52
CA12 O43570 3/20 0.52
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
CA4 P22748 3/20 0.52
CA7 P43166 3/20 0.52
CA9 Q16790 3/20 0.52
KDM4E B2RXH2 3/20 0.50
HMGB1 P09429 2/20 0.50
HPGD P15428 2/20 0.50
NAPRT Q6XQN6 2/20 0.50
HSD17B10 Q99714 2/20 0.50
ESR1 P03372 1/20 0.50
ITGB3 P05106 1/20 0.50
ITGA2B P08514 1/20 0.50
TSHR P16473 1/20 0.50
GGT1 P19440 1/20 0.50
PTGS1 P23219 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL1302034 1.00 ALDH1A1 (0.67) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL30894712 1.00 ALDH1A1 (0.67) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL36441 1.00 ALDH1A1 (0.67) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL5675293 0.98 ALDH1A1 (0.64) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL11417227 0.96 ALDH1A1 (0.61) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL1398185 0.92 ALDH1A1 (0.56) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL4599271 0.92 ALDH1A1 (0.56) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL11701993 0.92 ALDH1A1 (0.56) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL22074773 0.90 ALDH1A1 (0.74) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL29175574 0.90 ALDH1A1 (0.74) ALDH1A1ALOX15AKR1C3CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240158253-A1 Optically Stable Transparent Zinc Oxide for Dental Applications DEN-MAT HOLDINGS, LLC (US) 2024-05-16 US disclosed