Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25028530 | 1.00 | MAPT (0.46) | MAPTTP53SMN1; SMN2ROCK2ALOX5 | |
| SCHEMBL30248448 | 0.93 | MAPT (0.52) | MAPTTP53SMN1; SMN2ROCK2THRB | |
| SCHEMBL25028529 | 0.93 | MAPT (0.52) | MAPTTP53SMN1; SMN2ROCK2THRB | |
| SCHEMBL23768827 | 0.91 | MAPT (0.49) | MAPTTP53SMN1; SMN2KDM4EGFER | |
| SCHEMBL25028041 | 0.87 | ROCK2 (0.44) | MAPTSMN1; SMN2ROCK2KDM4EFAAH | |
| SCHEMBL30895162 | 0.87 | ROCK2 (0.44) | MAPTSMN1; SMN2ROCK2KDM4EFAAH | |
| SCHEMBL29978853 | 0.86 | MAPT (0.56) | MAPTTP53SMN1; SMN2KDM4EGFER | |
| SCHEMBL23769036 | 0.86 | MAPT (0.56) | MAPTTP53SMN1; SMN2KDM4EGFER | |
| SCHEMBL25028537 | 0.84 | ROCK2 (0.47) | MAPTTP53SMN1; SMN2ROCK2ALDH1A1 | |
| SCHEMBL30248596 | 0.84 | ROCK2 (0.47) | MAPTTP53SMN1; SMN2ROCK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118019738-A | Small molecule urea derivatives as STING antagonists | 库拉德夫制药私人有限公司 | 2024-05-10 | — | — | CN | claimed |
| US-20240360119-A1 | SMALL MOLECULE UREA DERIVATIVES AS STING ANTAGONISTS | CURADEV PHARMA PVT. LTD. (IN) | 2024-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240360119-A1 | SMALL MOLECULE UREA DERIVATIVES AS STING ANTAGONISTS | STING1, CGAS, SSB | MAPT 2509/4885TP53 2447/4885SMN1; SMN2 1263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.