Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30895272 | 0.87 | PDGFRA (0.38) | MAPK8ADORA2AADORA2BNT5ECASP3 | |
| SCHEMBL30895271 | 0.87 | PDGFRA (0.38) | MAPK8ADORA2AADORA2BNT5ECASP3 | |
| SCHEMBL17177295 | 0.85 | MAPK8 (0.40) | MAPK8ADORA2AADORA2BCASP3ELANE | |
| SCHEMBL28245972 | 0.77 | NT5E (0.41) | NT5ECASP3LMNACYP1A2CYP2D6 | |
| SCHEMBL1336984 | 0.75 | ADORA2A (0.59) | MAPK8ADORA2AADORA2BCASP3NPC1 | |
| SCHEMBL23535755 | 0.73 | MAPK8 (0.39) | MAPK8ADORA2AADORA2BCASP3ELANE | |
| SCHEMBL15970798 | 0.71 | MAPK8 (0.40) | MAPK8ADORA2AADORA2BCASP3ELANE | |
| SCHEMBL30895247 | 0.71 | IDO1 (0.38) | IDO1 | |
| SCHEMBL20176288 | 0.70 | MAPK8 (0.39) | MAPK8ADORA2AADORA2BCASP3ELANE | |
| SCHEMBL5316056 | 0.70 | MAPK8 (0.39) | MAPK8ADORA2AADORA2BCASP3ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608507-A1 | COMPOUNDS AND COMPOSITIONS AS GPR52 MODULATORS | Neurocrine Biosciences, Inc. (US) | 2025-09-03 | — | — | EP | disclosed |
| WO-2024091538-A1 | COMPOUNDS AND COMPOSITIONS AS GPR52 MODULATORS | NEUROCRINE BIOSCIENCES, INC. (US) | 2024-05-02 | — | — | WO | disclosed |