Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | NMT1 | P30419 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30895272 | 1.00 | PDGFRA (0.38) | PDGFRACDK5TYRO3MAPK8PDE2A | |
| SCHEMBL30895267 | 0.87 | MAPK8 (0.39) | PDGFRACDK5TYRO3MAPK8PDE2A | |
| SCHEMBL30895265 | 0.80 | ESR1 (0.40) | KMOADORA2AADORA2BSLC22A12CYP19A1 | |
| SCHEMBL2144982 | 0.75 | ADORA2A (0.59) | PDGFRACDK5TYRO3MAPK8NPC1 | |
| SCHEMBL30032217 | 0.75 | ADORA2A (0.59) | PDGFRACDK5TYRO3MAPK8NPC1 | |
| SCHEMBL28245972 | 0.73 | NT5E (0.41) | CASP3MPONT5ESLC22A12CYP2C9 | |
| SCHEMBL30895259 | 0.72 | HSD17B10 (0.36) | — | |
| SCHEMBL30895260 | 0.72 | HSD17B10 (0.36) | — | |
| SCHEMBL21163430 | 0.72 | PDGFRA (0.43) | PDGFRACDK5TYRO3MAPK8NPC1 | |
| SCHEMBL16596067 | 0.71 | GRM4 (0.43) | PDGFRACDK5TYRO3MAPK8NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608507-A1 | COMPOUNDS AND COMPOSITIONS AS GPR52 MODULATORS | Neurocrine Biosciences, Inc. (US) | 2025-09-03 | — | — | EP | disclosed |
| WO-2024091538-A1 | COMPOUNDS AND COMPOSITIONS AS GPR52 MODULATORS | NEUROCRINE BIOSCIENCES, INC. (US) | 2024-05-02 | — | — | WO | disclosed |