Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.48 |
| ▸ | JAK1 | P23458 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29789055 | 0.77 | TYK2 (0.61) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL20688655 | 0.69 | TYK2 (0.87) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL31021347 | 0.68 | TYK2 (0.44) | TYK2JAK1 | |
| SCHEMBL21948915 | 0.67 | TYK2 (0.77) | TYK2 | |
| SCHEMBL24263296 | 0.67 | TYK2 (0.78) | TYK2 | |
| SCHEMBL29754460 | 0.67 | TYK2 (0.78) | TYK2 | |
| SCHEMBL20689694 | 0.67 | TYK2 (0.63) | TYK2 | |
| SCHEMBL31218852 | 0.66 | TYK2 (0.62) | TYK2 | |
| SCHEMBL21285310 | 0.66 | TYK2 (0.45) | TYK2 | |
| SCHEMBL26532383 | 0.66 | TYK2 (0.64) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084920-A | Five membered heteroaromatic pyrimidine-3-carboxamide derivatives, compositions and uses thereof | 镇江圣安医药有限公司 | 2024-05-28 | — | — | CN | disclosed |