Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30240840 | 1.00 | TSHR (0.42) | TSHRALDH1A1MAPTTP53HPGD | |
| SCHEMBL31108201 | 1.00 | TSHR (0.42) | TSHRALDH1A1MAPTTP53HPGD | |
| SCHEMBL30240906 | 1.00 | TSHR (0.42) | TSHRALDH1A1MAPTTP53HPGD | |
| SCHEMBL30240800 | 1.00 | TSHR (0.42) | TSHRALDH1A1MAPTTP53HPGD | |
| SCHEMBL24933035 | 0.85 | TSHR (0.40) | TSHRALDH1A1MAPTTP53HPGD | |
| SCHEMBL24933450 | 0.85 | ALDH1A1 (0.42) | TSHRALDH1A1MAPTTP53HPGD | |
| SCHEMBL24933310 | 0.85 | ALDH1A1 (0.43) | TSHRALDH1A1MAPTTP53HPGD | |
| SCHEMBL30896290 | 0.85 | ALDH1A1 (0.43) | TSHRALDH1A1MAPTTP53HPGD | |
| SCHEMBL24933387 | 0.85 | ALDH1A1 (0.41) | TSHRALDH1A1MAPTTP53HPGD | |
| SCHEMBL30896278 | 0.85 | ALDH1A1 (0.43) | TSHRALDH1A1MAPTTP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | disclosed |