Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.45 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BCDIN3D | Q7Z5W3 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27261035 | 0.85 | EGFR (0.43) | HAO1PRMT5SCN9AHTR2AHTR2C | |
| SCHEMBL27260141 | 0.81 | SCN9A (0.44) | HAO1PPARGPRMT5SCN9AHTR2A | |
| SCHEMBL27260026 | 0.78 | PPARG (0.45) | HAO1PPARGPRMT5SCN9AHTR2A | |
| SCHEMBL31613196 | 0.76 | CYP1A2 (0.42) | HAO1BCDIN3D | |
| SCHEMBL27260447 | 0.76 | SCN9A (0.41) | HAO1PPARGPRMT5SCN9AHTR2A | |
| SCHEMBL30444577 | 0.74 | NOTUM (0.42) | HAO1PRMT5SCN9AHTR2AHTR2C | |
| SCHEMBL27260567 | 0.74 | SCN9A (0.41) | HAO1PRMT5SCN9AHTR2AHTR2C | |
| SCHEMBL7550492 | 0.74 | KDR (0.43) | PPARG | |
| SCHEMBL27260137 | 0.74 | SCN9A (0.41) | HAO1GAAPPARGPRMT5SCN9A | |
| SCHEMBL7550488 | 0.74 | KDR (0.43) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612128-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF HEMOGLOBINOPATHIES | Bristol-Myers Squibb Company (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024097932-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF HEMOGLOBINOPATHIES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-10 | — | — | WO | disclosed |