Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 6/20 | 0.36 |
| ▸ | PDE1A | P54750 | 5/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 5/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30896414 | 0.93 | PIK3CD (0.39) | PIK3CDPDE4DMAPK1KMT2AL3MBTL1 | |
| SCHEMBL16898982 | 0.92 | MAPT (0.38) | PIK3CDMAPK1MAPT | |
| SCHEMBL16899208 | 0.90 | MAPT (0.37) | PIK3CDMAPK1KMT2AMAPTPDE9A | |
| SCHEMBL30896408 | 0.84 | PIK3CD (0.39) | PIK3CDPDE4DMAPK1PDE1CPDE1A | |
| SCHEMBL30959605 | 0.82 | RXRA (0.47) | MAPK1KMT2AMAPT | |
| SCHEMBL21797036 | 0.82 | RXRA (0.47) | MAPK1KMT2AMAPT | |
| SCHEMBL27228529 | 0.77 | RXRA (0.47) | PIK3CDMAPK1KMT2AL3MBTL1MAPT | |
| SCHEMBL30860939 | 0.77 | RXRA (0.47) | PIK3CDMAPK1KMT2AL3MBTL1MAPT | |
| SCHEMBL30122245 | 0.76 | PIK3CD (0.47) | PIK3CDPDE4DMAPK1PDE1CPDE1A | |
| SCHEMBL16898881 | 0.75 | SLC18A3 (0.32) | PIK3CDPDE4DMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612128-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF HEMOGLOBINOPATHIES | Bristol-Myers Squibb Company (US) | 2025-09-10 | — | — | EP | disclosed |
| CN-120129677-A | Compounds and their use for the treatment of heme lesions | 百时美施贵宝公司 | 2025-06-10 | — | — | CN | disclosed |
| WO-2024097932-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF HEMOGLOBINOPATHIES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-10 | — | — | WO | disclosed |