Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20985953 | 0.86 | PKM (0.57) | PKMALDH1A1BRD4KCNH2MAPT | |
| SCHEMBL11797084 | 0.84 | PKM (0.64) | PKMALDH1A1BRD4KCNH2MAPT | |
| SCHEMBL19911377 | 0.81 | PKM (0.64) | PKMALDH1A1BRD4KCNH2MAPT | |
| SCHEMBL9570463 | 0.80 | PKM (0.70) | PKMALDH1A1BRD4KCNH2MAPT | |
| SCHEMBL7034458 | 0.79 | PKM (0.68) | PKMALDH1A1BRD4KCNH2MAPT | |
| SCHEMBL19911366 | 0.79 | PKM (0.68) | PKMALDH1A1BRD4KCNH2MAPT | |
| SCHEMBL19911365 | 0.78 | PKM (0.60) | PKMALDH1A1BRD4KCNH2MAPT | |
| SCHEMBL1539112 | 0.78 | PKM (0.60) | PKMALDH1A1BRD4KCNH2MAPT | |
| SCHEMBL9039302 | 0.78 | PKM (0.67) | PKMALDH1A1BRD4KCNH2MAPT | |
| SCHEMBL19911400 | 0.78 | PKM (0.60) | PKMALDH1A1BRD4KCNH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024078569-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2024-04-18 | — | — | WO | disclosed |