SCHEMBL30898264

SCHEMBL30898264

CC(C)(C)OC(=O)NCc1cccc(COS(C)(=O)=O)c1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GLS O94925 5/20 0.49
BRD9 Q9H8M2 1/20 0.47
BAZ2B Q9UIF8 1/20 0.47
BAZ2A Q9UIF9 1/20 0.47
CA1 P00915 2/20 0.46
CA12 O43570 1/20 0.46
CA7 P43166 1/20 0.46
CA14 Q9ULX7 1/20 0.46
BRD4 O60885 3/20 0.44
KDM4A O75164 1/20 0.43
CREBBP Q92793 1/20 0.43
SYK P43405 1/20 0.43
NQO2 P16083 1/20 0.43
NAMPT P43490 2/20 0.41
CA2 P00918 1/20 0.41
GAA P10253 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
HDAC1 Q13547 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16785102 1.00 GLS (0.49) GLSBRD9BAZ2BBAZ2ACA1
SCHEMBL30898273 0.88 NQO2 (0.52) GLSCA1CA12CA7CA14
SCHEMBL19716620 0.87 CA1 (0.50) BRD9BAZ2BBAZ2ACA1CA12
SCHEMBL30898285 0.85 NQO2 (0.47) CA1CA12NQO2CA2
SCHEMBL1025076 0.82 SIRT2 (0.48) CA1CA12CA7CA14SYK
SCHEMBL13315979 0.82 GLS (0.52) GLSBRD9BAZ2BBAZ2ACA1
SCHEMBL1165088 0.81 GLS (0.55) GLSBRD9BAZ2BBAZ2ACA1
SCHEMBL8342682 0.81 GLS (0.55) GLSBRD9BAZ2BBAZ2ACA1
SCHEMBL13981921 0.81 GLS (0.55) GLSBRD9BAZ2BBAZ2ACA1
SCHEMBL16181822 0.81 GLS (0.55) GLSBRD9BAZ2BBAZ2ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024105159-A1 LIGANDS OF THE M6A-RNA READERS UNIVERSITY OF ZURICH (CH) 2024-05-23 WO disclosed