Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3729107 | 0.78 | MAPT (0.78) | MAPTALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL30282807 | 0.78 | HTT (0.74) | MAPTALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL30287480 | 0.78 | POLB (0.74) | MAPTALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL3725459 | 0.78 | POLB (0.74) | MAPTALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL3736372 | 0.78 | MAPT (0.61) | MAPTALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL3729052 | 0.78 | HTT (0.74) | MAPTALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL3728335 | 0.75 | MAPT (0.62) | MAPTALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL3723685 | 0.75 | MAPT (0.58) | MAPTALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL25153570 | 0.75 | RAB9A (0.58) | MAPTALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL3729134 | 0.74 | MAPT (0.57) | MAPTALDH1A1HPGDRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118055930-A | Thiadiazole derivative, composition and application thereof | 北京丹擎医药科技有限公司 | 2024-05-17 | — | — | CN | disclosed |