Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.70 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.70 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.70 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29223625 | 1.00 | GABRA1 (0.70) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL1021821 | 0.85 | GABRA1 (0.80) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL17338645 | 0.83 | GABRA1 (0.79) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL7728970 | 0.83 | GABRA1 (1.00) | GABRA1GABRB2GABRB1GABRA3 | |
| SCHEMBL2031515 | 0.82 | GABRA1 (0.59) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL17338522 | 0.82 | GABRA1 (0.75) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL7291769 | 0.82 | GABRA1 (1.00) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL17338625 | 0.81 | GABRA1 (0.80) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL17338558 | 0.80 | GABRA1 (0.75) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL11141839 | 0.80 | GABRA1 (0.70) | GABRA1GABRB2GABRB1GABRA3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924169-A | Dihydroquinoline derivative and pharmaceutical application thereof in resisting influenza | 山东大学齐鲁医院 | 2024-04-26 | — | — | CN | disclosed |