Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.56 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.44 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3880477 | 1.00 | L3MBTL1 (0.59) | L3MBTL1KDM4EIP6K1ACVR1ALDH1A1 | |
| SCHEMBL30186355 | 0.86 | ESR1 (0.62) | L3MBTL1KDM4EIP6K1ACVR1ALDH1A1 | |
| SCHEMBL29607244 | 0.81 | L3MBTL1 (0.60) | L3MBTL1KDM4EIP6K1ACVR1ALDH1A1 | |
| SCHEMBL7600132 | 0.81 | L3MBTL1 (0.60) | L3MBTL1KDM4EIP6K1ACVR1ALDH1A1 | |
| SCHEMBL3230513 | 0.79 | L3MBTL1 (0.59) | L3MBTL1KDM4EIP6K1ACVR1ALDH1A1 | |
| SCHEMBL9919058 | 0.79 | L3MBTL1 (0.59) | L3MBTL1KDM4EIP6K1ACVR1ALDH1A1 | |
| SCHEMBL9922439 | 0.79 | L3MBTL1 (0.59) | L3MBTL1KDM4EIP6K1ACVR1ALDH1A1 | |
| SCHEMBL9919060 | 0.79 | L3MBTL1 (0.59) | L3MBTL1KDM4EIP6K1ACVR1ALDH1A1 | |
| SCHEMBL422211 | 0.79 | L3MBTL1 (0.59) | L3MBTL1KDM4EIP6K1ACVR1ALDH1A1 | |
| SCHEMBL31723363 | 0.79 | L3MBTL1 (0.59) | L3MBTL1KDM4EIP6K1ACVR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4634171-A1 | PROCESS FOR THE PREPARATION OF A QUINAZOLINONE DERIVATIVE | F. Hoffmann-La Roche AG (CH) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024126634-A1 | PROCESS FOR THE PREPARATION OF A QUINAZOLINONE DERIVATIVE | F. HOFFMANN-LA ROCHE AG (CH) | 2024-06-20 | — | — | WO | disclosed |