Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 2/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.37 |
| ▸ | AKT1 | P31749 | 2/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.33 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30898671 | 0.84 | SLC18A3 (0.37) | EZH2PDE4BCCNCCDK8HASPIN | |
| SCHEMBL30898645 | 0.76 | EZH2 (0.41) | EZH2MAP4K1CTSC | |
| SCHEMBL30898619 | 0.73 | MAPK14 (0.57) | EZH2 | |
| SCHEMBL30898621 | 0.73 | MAPK14 (0.57) | EZH2 | |
| SCHEMBL22471368 | 0.71 | EZH2 (0.69) | EZH2 | |
| SCHEMBL30898614 | 0.70 | BRD4 (0.40) | PDE4BAKT1MEN1KMT2A | |
| SCHEMBL30898661 | 0.70 | BRD4 (0.40) | PDE4BAKT1MEN1KMT2A | |
| SCHEMBL22471588 | 0.69 | PIK3CA (0.45) | AKT1NOTUMPIK3CAACLY | |
| SCHEMBL24219917 | 0.69 | EZH2 (0.68) | EZH2 | |
| SCHEMBL30898657 | 0.68 | TDP2 (0.38) | PDE4BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113330008-B | Preparation method of amide compound and application of amide compound in medicine field | 上海华汇拓医药科技有限公司 | 2024-05-07 | — | — | CN | disclosed |