Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | STS | P08842 | 1/20 | 0.50 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL581359 | 0.88 | KMT2A (0.65) | KMT2AMEN1ENPP2GAASMN1; SMN2 | |
| SCHEMBL10014912 | 0.87 | MEN1 (0.61) | KMT2AMEN1ENPP2L3MBTL1TDP1 | |
| SCHEMBL30899146 | 0.87 | MEN1 (0.61) | KMT2AMEN1ENPP2L3MBTL1TDP1 | |
| SCHEMBL30899144 | 0.84 | MEN1 (0.64) | KMT2AMEN1ENPP2GAAL3MBTL1 | |
| SCHEMBL9254874 | 0.80 | KDM4E (0.65) | KMT2AMEN1GAAL3MBTL1TDP1 | |
| SCHEMBL2231773 | 0.80 | KMT2A (0.51) | KMT2AMEN1ENPP2GAAL3MBTL1 | |
| SCHEMBL19478884 | 0.79 | MEN1 (0.61) | KMT2AMEN1ENPP2GAAL3MBTL1 | |
| SCHEMBL5865527 | 0.79 | STS (0.52) | SMN1; SMN2NPC1RAB9ASTSCA2 | |
| SCHEMBL8794066 | 0.79 | MEN1 (0.82) | KMT2AMEN1ENPP2GAAL3MBTL1 | |
| SCHEMBL11983376 | 0.79 | CA12 (0.59) | KMT2AGAAL3MBTL1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063355-A | Preparation method of high-purity adapalene intermediate 6- (p-toluenesulfonyloxy) -2-naphthoate | 杭州善礼生物医药科技有限公司 | 2024-05-24 | — | — | CN | disclosed |