Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | BRD4 | O60885 | 3/20 | 0.41 |
| ▸ | BRD2 | P25440 | 3/20 | 0.41 |
| ▸ | BRD3 | Q15059 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27199057 | 0.88 | CNR2 (0.48) | CNR1CNR2POLBSMN1; SMN2LMNA | |
| SCHEMBL24512148 | 0.86 | CNR1 (0.46) | CNR1CNR2POLBSMN1; SMN2LMNA | |
| SCHEMBL29717121 | 0.86 | CNR1 (0.46) | CNR1CNR2POLBSMN1; SMN2LMNA | |
| SCHEMBL29717201 | 0.84 | LMNA (0.55) | CNR1CNR2SMN1; SMN2LMNABRD4 | |
| SCHEMBL29717142 | 0.84 | LMNA (0.52) | CNR1CNR2SMN1; SMN2LMNABRD4 | |
| SCHEMBL30899260 | 0.84 | CNR2 (0.44) | CNR1CNR2POLBSMN1; SMN2LMNA | |
| SCHEMBL24512122 | 0.84 | CNR2 (0.44) | CNR1CNR2POLBSMN1; SMN2LMNA | |
| SCHEMBL29717169 | 0.83 | BRD4 (0.54) | CNR1CNR2SMN1; SMN2LMNABRD4 | |
| SCHEMBL24512245 | 0.81 | CNR1 (0.64) | CNR1CNR2SMN1; SMN2LMNABRD4 | |
| SCHEMBL29717111 | 0.81 | CNR1 (0.64) | CNR1CNR2SMN1; SMN2LMNABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117915903-A | Compounds for the treatment of neurodegenerative, degenerative and metabolic disorders and uses thereof | 佛罗里达大学研究基金会公司 | 2024-04-19 | — | — | CN | disclosed |